Durviz, intermediary between Mission Bio and the Josep Carreras center


Durviz acts as an intermediary in the current collaboration between Mission Bio and the Josep Carreras Research Center. A job that makes us proud because it is a new acknowledgment of the work that we have been developing for years in the health research sector.


Durviz, intermediary between Mission Bio and the Josep Carreras center

Durviz has been key in the collaboration established by Mission Bio and the Josep Carreras Research Center in Barcelona. A space in which fundamental work will be carried out that will be a boost to our trajectory and a challenge for the future of cancer research

Mission Bio: What is it?

Mission Bio is the name of a US company dedicated to performing high-throughput single-cell DNA and multi-omic analyses. Its main goal is to help researchers and clinicians unlock single-cell biology to enable the discovery, development, and delivery of precision medicine.

It should be noted, at this point, that through its centers of excellence, Mission Bio partners with leaders within the solid tumor and hematologic malignancy research communities. All this with the aim of continuing to build and refine the functionality of Tapestri, the only equipment available on the market capable of simultaneously analyzing DNA and other analytes such as cell surface proteins at the level of a single cell, through its exclusive two-step microfluidic technology.

Its international development and search for alliances has led it to create the first and only Center of Excellence in Europe, located at the Josep Carreras Leukemia Research Institute. A space that will be directed by the renowned doctor Manel Esteller.


Josep Carreras Research Center

The Josep Carreras Research Institute is the first European research center specializing in leukemia and other blood cancers.

Its main research objective is the identification of new therapeutic targets; as well as in the development of more precise and less aggressive treatments by understanding the origin and development of leukemia and other blood cancers.

Manuel Esteller, director of the Josep Carreras Institute, is the author of more than six hundred original publications in peer-reviewed scientific journals. At the same time he is editor-in-chief of “Epigenetics”, and a member of the editorial board of Genome Research. Also, last year, he co-authored a paper in Experimental Hematology. This discussed the benefits of single cell analysis to characterize heterogeneity. Also of the clonal evolution of blood cell subpopulations in myeloid and lymphoid cancers. Some results that can improve the diagnosis of patients, risk stratification and the prescription of targeted therapies.

As Mission Bio’s second single-cell Tapestri Center of Excellence, and the first in Europe, the Josep Carreras Institute will inform academic and industry best practices. It will do this using single cell and multi-omic DNA sequencing in haematological malignancy research. At the same time, it will launch a new program in breast cancer.


The Josep Carreras Institute has long been a benchmark in the development of single-cell analysis and launched a specialized unit in 2021.


The partnership with Mission Bio will boost the Josep Carreras Institute’s application of single-cell DNA sequencing to investigate disease progression. Also its therapeutic resistance and measurable residual disease (MRD) both in blood cancers and in its innovative breast cancer research program.


Durviz as intermediary with Mission Bio

Durviz has been working hand in hand with Mission Bio and the Josep Carreras Foundation for years. And he will be responsible for supplying everything needed to carry out the investigations with Tapestri, Mission Bio’s revolutionary team. A group with which clonal mosaicism and neoplastic transition, clonal evolution, can be questioned. But also metastatic spread with its ability to co-detect SNV and CNV at the single cell level in a scalable manner.

This is very important since it is a tool that allows us to understand resistance to diseases. So users can detect rare emerging clones early. And do it with reliable and sensitive measures of loss of heterozygosity. Which helps them understand how driver mutations are acquired over time that can allow tumor escape and metastasis.

It is also critical for developing single-cell multi-omics analysis. This is of growing importance in oncology precision medicine as it sheds light on the clonal structure of tumors to guide combination therapeutic development and personalized treatment.

A job in which we at Durviz are delighted to participate.

Real Saliva Collection


Real Saliva Collection and transport device is a product that allows the collection and storage of saliva samples at room temperature. Without losing any of their composition, which is an advantage for laboratories since they must not use expensive refrigeration systems to maintain them while they do their work.

So that you know more about it, we have written this article with which we want to encourage you to try it.

Real Saliva Collection and transport device is a Real brand product designed for laboratory use. A space in which it is necessary to have practical solutions that streamline procedures without having to subject the samples to complex conservation systems.

In this sense, Real Saliva Collection and transport device has been designed for the collection and conservation of saliva samples at room temperature. And all this is done in a simple and non-invasive way. So the sample does not suffer any alteration that could change the results after the process to which it is subjected.

For this reason, the Real Saliva Collection and transport device saliva collection tube is sent to the laboratory for DNA extraction so that from then on the analysis can be done using the REALPURE SALIVA KIT or other purification kits of the mark. And it is that we have many products in this sense and you can know them through the Durviz website. In this space, we even share detailed information about the characteristics of each one of them so that you can get an idea of ​​all the applications and possibilities they offer.

Saliva samples stored with the Real Saliva Collection and transport device are stable at room temperature and keep in this way for more than 2 years. A very long time when compared to other similar products that we can find in the market and that other companies make.

How Real Saliva Collection works

To properly use the Real Saliva Collection, the steps outlined in its procedure must be scrupulously followed. Information that reaches the user in the form of a paper brochure and that we summarize below so that you can get an idea of ​​its exactness.

The steps and details that must be taken into account when using the Real Saliva Collection and transport device are the following:

  1. The person from whom a saliva sample is to be taken should not eat, chew gum, drink or smoke for 30 minutes prior to taking the sample.
  2. It is advisable to wash your mouth with water and wait for 10 minutes.
  3. To stimulate the secretion of saliva, it is convenient to rub the cheeks and brush the palate with the tongue.
  4. When we are ready to collect the sample, place the funnel in the saliva collection tube. Spit the saliva into the funnel until the liquid (not including bubbles) reaches the 2 milliliter line on the collection tube. If there is an excess of bubbles, we must remove them by gently tapping the tube on a hard surface.
  5. Remove the blue cap from the Saliva preservative solution.
  6. Add the saliva preservative solution to the collection tube.
  7. Tightly close the saliva collection tube.
  8. Shake for 15 seconds to mix.
  9. The saliva sample is from that moment preserved and ready to be stored, sent somewhere or processed.

Now that you know the product, you have to encourage yourself to try it. You will certainly not be disappointed. And if despite all this information you have any questions or want to ask us a question, do not hesitate and get in touch with us. We will be delighted to assist you.

INTELSIUS PathoPak, biological samples container

INTELSIUS PathoPak is a revolutionary container specially designed for biological samples. Hence, it is one of the preferred products by professionals who work in laboratories around the world. Especially now with the great workload that has flourished as a result of Covid 19. And this container is also suitable for the transport of these samples.

So that you can know its main characteristics and how it should be handled correctly, at Durviz we have written this article in which we explain all the basic data.


INTELSIUS PathoPak, biological samples container

PathoPak is a container for biological samples characterized by its residence and easy handling. A work that has been possible thanks to the research of the Intelsius brand, responsible for its manufacture.

In addition, it is a highly durable and protective product that is ergonomically designed with an equal circumference throughout. What facilitates the packaging and the extraction of the samples that are manipulated in the laboratory work.

It is a product suitable for shipping a wide range of primary products, including: blood tubes, sample containers, swabs, collection bags or for blood transfusion; as well as medical devices. All this makes PathoPack a rigid reusable system but also a cost-effective solution for laboratory work.

Specific features of PathoPak

PathoPak solutions are available in three different sizes. These are: 1 liter, 2 liter and 3 liter, ensuring that the payload can be conveniently stored in the chosen solution. Which in turn leads to the minimization of volumetric weight and reduces transportation costs.

For added content security, the PathoPak screw cap takes one and a half turns to open. In addition, it has a non-conical opening so that an easy extraction of the samples we have collected can be developed.

All sizes of PathoPak are suitable for the compliant transport of UN3373 Category B infectious substances. Of course, using innovative features.

If you want to check its effectiveness, you can request samples. Simply contact a member of our customer service team or check out our blog for the latest news and information on IATA and ADR dangerous goods transport regulations.

In this sense, it must also be remembered that it is a product suitable for complete Category A and Category B solutions.


Supplied components

All PathoPak packages contain the following:

  • A rigid secondary pressure vessel of 95kPa that complies with IATA, the most demanding on the market.
  • An outer box printed according to the transport regulations.
  • An absorbent.
  • Bubble wrap.
  • Infectious class label.
  • Label with security seal.
  • Information about the PathoPak product range in case you need anything else.


Guaranteed product

The PathoPak range is certified by the UN for category A shipments, complying at all times with IATA, ADR and CFR 49 (DOT) transport regulations. And also ensuring optimal protection for your sample regardless of its classification.

Additionally, each PathoPak has met and passed UN performance testing criteria, allowing any primary container to be transported.

For all this, at Durviz we put it at your fingertips, aware that with this we are going to facilitate many daily lab work tasks.

Mission Bio Exclusive Virtual Event

Date: Tuesday, September 21, 2021

Time: 8:00 a.m. PST | 11:00 a.m. EST | 5:00 p.m. CET


Join a virtual event with Mission Bio to learn highlights of the Tapestri Platform expansion and learn how to study single cells in less time with less sample input, enabling new avenues of research previously impossible.


We will be joined by Dr. Koichi Takahashi, MD Anderson Cancer Center, who will share his work in leukaemia research using novel multi-omics applications.

More information

Visit our online shop, products in stock with inmediate delivery

In our online shop you will find a wide range of products for COVID diagnostic as well as offers and flash promotions
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Collection stabilization and transport of saliva samples

Transport of saliva samples and other cares

Collection, stabilization, and transport of saliva samples are important now more than ever. And it is that since we live in the middle of a pandemic, care in the entire process of extraction and handling of samples requires greater neatness. Therefore, we need products that facilitate procedures. A job that companies like Real offer to professionals in the sector.

Collection stabilization and transport of saliva samples

Collection, stabilization and transport of saliva samples

Collecting samples for analysis requires precise conditions to prevent contamination. And is that any interference can condition the results. What cancels the test and makes the procedure unfeasible.

To avoid this situation, the Real company has launched REAL SALIVA VIRAL Sample Collection Kit. A product that provides an all-in-one procedure. And to be able to do with it a fast and safe collection; as well as to ensure its stabilization and the transport of one-milliliter saliva samples. And all can be done at room temperature, as the product stabilizes the viral DNA and RNA.

This stabilization is possible thanks to REAL VIRAL Stabilization Solution. A product that efficiently inactivates viruses. What solutions for the handling of non-infectious samples, making possible a safe handling and shipment of all these tests.

One of the main advantages of this system is that the samples are kept at room temperature. In the case of DNA, up to one year. Regarding RNA, up to a month. In case they are subjected to low temperatures, the conditions change. And it is that if they are kept between -20 / -80 ° C they can be kept indefinitely.

Collection stabilization and transport of saliva samples

Advantages of the Real Saliva collection and stabilization system

The main advantages of the sample collection, stabilization and transport system developed by the Real company are the following:

  • Allows the handling of samples of one milliliter of saliva.
  • Inactivates microorganisms and viruses for easy and safe handling and transport.
  • It is a product that allows the isolation of human genomic DNA and viral DNA / RNA. A variety not offered by other similar products on the market.
  • As already mentioned, this product allows transport at room temperature. This means eliminating cold infrastructure elements that hinder and retain transportation by requiring more procedures and paperwork.
  • Makes it possible to preserve total DNA in samples, including viral DNA, at room temperature. But if a temperature between 4º-25ºC is kept, it will be possible to do so for a whole year.
  • In the case of RNA there are very interesting advantages. And it is that it allows total RNA to be preserved, including viral RNA, at room temperature. And if we do it in a cold system (those that are between 4º-25ºC can be kept for a whole month.
  • They are systems compatible with most of the DNA and RNA isolation methods found on the market. Although it is best to use REAL products. Both those offered as kits and those sold independently.
  • It is a product specially designed for health professionals. And its handling is very simple and intuitive.


So, if you are looking for a collection, stabilization and transport system for any of your saliva samples, at Durviz we have what you need. Do not hesitate, visit our website to expand this information and get in touch with us.

Rapid COVID 19 test from blood, serum or plasma

If you need to do a rapid COVID 19 detection test from blood, serum or plasma samples, at Durviz we have the product you need. It is an exclusive proposal for use in laboratories


Rapid COVID 19 test from blood, serum or plasma

The rapid test that we propose at Durviz is a lateral flow chromatographic immunoassay that allows the qualitative detection of IgG and IgM antibodies against 2019-nCoV. An action that it is capable of carrying out in human blood, serum, plasma or also in a blood sample with a lancet.

This product uses immunochromatography as a detection technique. These types of tests are commonly used for medical diagnosis both for home tests and for use in the laboratory. Hence, it is one of the most requested media by professionals at the present time.

And it is that immunochromatography is one of the most widely used immunodiagnostic techniques today. Its main attractions are: the simplicity and speed of the tests that use this proposal. Hence, with the current need for diagnoses due to the COVID 19 pandemic, there are more and more applications of this technique in the field of tests. Especially since it does not need reagents or additional instrumentation for its operation. Something that does occur in other similar methodologies that are applied to the clinical field.


Advantages of the rapid COVID 19 test

The main advantages of this product are the following:

  • It is presented in a strip format, in which the test sample flows along a solid substrate through capillary action.
  • This is a combined antibody test that can provide information on the stage of infection of the person being tested. And it is that the detection of COVID-19 IgM antibodies tends to indicate a recent exposure to COVID-19, while the detection of COVID-19 IgG antibodies indicate a later stage of infection.
  • The test contains anti-human IgM and anti-human IgG as capture reagent, 2019-nCoV antigen as detection reagent. An IgG reagent is used in the control line system.
  • It is a product for exclusive use in laboratories.


To all this must be added, in addition, that IgM provides the first line of defense during viral infections, followed by the generation of adaptive responses of high anity of IgG for long-term immunity and immunological memory.


COVID 19 Rapid Test Features

The main features of the COVID 19 rapid test are as follows:

  • Testing should be done immediately after samples have been collected.
  • Serum and plasma samples can be stored at 2-8 ° C for up to 7 days. For long-term storage, serum / plasma samples should be kept below -20 ° C. Whole blood collected by venipuncture should be stored at 2-8 ° C if testing will be performed within 2 days of collection.
  • Negative results do not rule out SARS-CoV-2 infection. This should be taken into account particularly in those people who have been in contact with the virus. A follow-up test with a molecular diagnosis should be considered to rule out infection in these individuals.
  • Results of antibody tests should not be used as the sole basis for making a diagnosis. Neither to exclude a SARS-CoV-2 infection or to report infection status.


So, if you are looking for a system that allows you to perform a rapid test to detect the presence of COVId 19 from blood, serum or plasma, do not hesitate and visit our website. You can buy both this product that we have reviewed in this article, as well as many other accessories. Everything so that you can acquire the best and most reliable results in your laboratory.

INTRON: DNA/ARN Virus Purification Kit

Intron is a DNA and RNA extraction kit that is designed for the rapid and sensitive isolation of either of these two substances from a variety of pathogens such as viruses, bacteria, etc.

It’s a versatile product. In fact, it works with all kinds of samples. Hence we can use it with plasma, with fresh or frozen blood (treated with anticoagulants other than heparin), with serum, with other body fluids free of cells and cells or tissues that have been infected with pathogens.
This DNA and RNA extraction kit is specifically designed to isolate high-quality nucleic acids from a variety of pathogens and samples using low elution and volumes that allow sensitive downstream analysis.
Once used, RNA or purified DNA is free of proteins and nucleases, thus being suitable for use in subsequent pathogen detection applications.

The DNA or RNA extraction kit uses the caxotropic salt in the immediately inactive lysis buffer DNasa or RNasa to ensure isolation of any of them intact. This also entails: greater efficiency of lysis (by not requiring additional additives), performing stable DNA or RNA extraction from various pathogenic samples; use a method without phenol and without the need for EtOH precipitation, and to be able to have in our laboratory the possibility of properly performing the extraction of samples in situations as disparate as forensic medicine or the diagnosis of diseases, among others.

To achieve all this, this extraction kit uses advanced silica gel membrane technology that allows for rapid and effective purification of DNA or RNA without organic extraction or precipitation with ethanol.  In addition, the damping conditions are finely adjusted to provide optimal DNA or RNA binding to the spine.

DNA and RNA extraction Kit Protocol

The procedure instructions for the extraction kit are very simple; allowing its users  to purify DNA or RNA from a wide variety of target sources in as little as 30 minutes. In fact, it is as follows:
1. Transfer 150 (300) μl  of plasma, serum, urine, cell culture supernatant, cell-free fluid or virus infection into tissue or cell in the 1.5 ml microcentrifuge tube.
If the volume of the sample is less than 150 L, the sample should be set to 150 L with WATER treated with DEPC. If the volume of the sample is higher, 15 ml. centrifugal tube should be used.
2. Add 300 (600) μl  lysis buffer. If the volume changes, vary the quantity.
3. Mix by stirring in vortex for 15 seconds.
4. Incubate at room temperature (15-25 °C) for 10 minutes.
5. Add 300 (600) μl joining buffer and mix gently.
If the sample volume is greater than 150 He, we should increase the amount of bonding buffer.
6. Place a rotating column in a 2 ml collection tube provided.
7. Load the lyses into the column and centrifuge at 13,000 rpm for 1 minute.
8. Dispose of the solution in the collection tube and place the column back in the same 2 ml. collection tube.
9. Add 500 μl  of wash buffer A, to the column and centrifuge for 1 minute at 13,000 rpm.
10. Dispose of the solution in the collection tube and place the spin column back into the same 2 ml. collection tube.
11. Add 500 μl  of wash buffer B to the column and centrifuge for 1 minute at 13,000 rpm.
12. Discard the solution in the collection tube and place the spin column back into the same 2 ml. Centrifuge collection tube for 1 minute at 13,000 rpm.It is important to dry the membrane as residual ethanol may interfere with downstream reactions.
13. Place the column in a 1.5 ml microcentrifuge tube without RNasa (not included), and add 30 – 60 l of elution buffer directly onto the centrifuge column membrane. It is important to dry the membrane as residual ethanol may interfere with downstream reactions. Do not touch the membrane with the tip of the pipette.
14. Incubate at room temperature for 1 minute, then centrifuge for 1 minute at 13,000 rpm.
15. Use 2-5 μl of elued solution as a template for PCR or RT-PCR.

DNA and RNA extraction kit. Durviz S.L.

In case you are interested or interested in purchasing this product, please contact us, Durviz.

Biocomma. Durviz S.L.


Biocomma is a means of transporting and preserving any virus (virus inactivation). A proposal with which it is possible to carry out the collection of samples, avoiding the risk of aerosol infection.

Y is that Biocomma is a solution that allows to inactivate the virus sample in time avoiding infections and protecting the RNA from degradation.

This system can be used for the collection and transport of samples from: clinical influenza, avian influenza, HFMD, measles and other virus samples as well as mycoplasma, ureaplasma, chlamydia and other samples.


Biocomma: Operation

The process we must follow when using Biocomma is as follows:

  1. Write the information that we consider important regarding the sample on the label. We must do this before we take the shot.
  2. Depending on the purpose of the analysis, the swab may be used to collect samples from the relevant parts.
  3. Put the swab in the preservation solution immediately after we have taken the samples. Then you have to break the swab rod and finally close the lid firmly.
  4. Once the samples have been taken, they must be transported to the laboratory within two working days of collection. The storage temperature should range from 2 to 8 °C. If it cannot be delivered to the laboratory within 48 hours, it must be stored at -70°C or less, and ensure that the collected samples are delivered to the relevant laboratory within 1 week. In any case, we should avoid repeated freezing-thawing cycles.
  5. If the samples cannot be analyzed within 24 hours of collection, they must be stored at -70°C or lower (if there are no storage conditions at -70°C, they should be temporarily stored in the refrigerator at -20°C).
  6. Samples used for virus isolation and nucleic acid detection should be processed as soon as possible.
Only by following these steps will we make the results we obtain from our samples as faithful as possible.
Biocomma. Durviz S.L.

Biocomma application

Sampling method

There are two sampling methods we will be able to use with Biocomma. The following:

a) Nasal hisopo. To do this simply gently insert the swab head into the nasal canal, remain for a while, then slowly turn outwards. Take a sample from the other side of the nostril with another sample, immerse the sample head in the preservation solution, break the sample rod and discard the top rod.

b) Throat torunda. In this case, just take a torunda of the bilateral pharyngeal tonsils and the back wall of the pharynx, submerging the head of the torunda in the preservation solution, break the rod of the torunda and discard the upper rod.


It should also be borne in mind that the use of Biocomma should not be carried out in the following cases:

– It is not a product for internal or external use in humans or animals.
– Not to be ingested.
– It’s irritating to the eyes and skin. If it accidentally splashes in your eyes, we should rinse with water.
– We must maintain ventilation during use.
– This product is a colourless, clear liquid. If the properties change, such as yellow, it should not be used
– This product is for in vitro diagnostics only.
– The liquid in the sampling tube is the means for transport, so it is important that it is present and in good condition.
– Waste from the sample collection solution will be sterilized.
– No leak.
If you need or want to benefit from the benefits of this product contact us, Durviz.

Covid-19 quick test for IgG/IgM detection

You can now find covid-19 quick test for IgG/IgM detection in Durviz. An immuno lateral flow chromatographic assay for the qualitative detection of IgG and IgM antibodies against 2019-nCoV in human blood, serum, plasma or also in a lancet blood sample. This puts at our fingertips an effective method for rapid diagnosis of COVID-19 infection in the person undergoing the test.

And all this doing a comprehensive analysis of the composition of the elements in the blood. So the detection of COVID-19 IgM antibodies tends to indicate recent exposure to COVID-19, while detection of COVID-19 IgG antibodies indicate a later stage of infection. Information needed to perform epidemiological studies, as well as the degree of involvement the disease had on the person.
And it is widely accepted that IgM provides the first line of defense during viral infections, followed by the generation of IgG’s high-anity adaptive responses for long-term immunity and immune memory.
Covid-19 quick test

Covid-19 quick test: IgM efficiency

Immunochromatography is one of the most relevant immunodiagnostic techniques out there. Its main advantages are: the simplicity and speed of the test.
Y is that more and more applications are being made of this technique, both in the field of tests, because no reagents or additional instrumentation are necessary; and in the clinical field.
This action can be performed using a simple device developed to detect the presence (or absence) of a target compound in the sample (the matrix). Element that makes up this test. It consists of two components: an IgG and an IgM, which allow to detect the presence of IgG and IgM antibodies independently.
Its operation is simple and very effective since the region of the IgG detection line is coated by human anti-IgG, and when depositing the sample in the analysis area, the possible IgG anti 2019-nCoV present, react with colored particles coated with antigens of 2019-nCoV present in the cassette. The mixture migrates through the membrane by capillary and reacts with human anti-IgG antibodies in the test region reserved for IgG detection. If the sample contains IgG antibodies for 2019-nCoV, a colored line appears in the designated region of IgG as a result of this antigen-antibody bonding reaction.
Similarly, in the IgM detection line, human anti-IgM antibodies are attached, in the case of a positive sample for IgM from 2019-nCoV, the complex formed together with the 2019-nCoV antigens reacts with the anti-IgM antibodies and a colored line appears in the corresponding region.
If the sample contains neither IgG nor IgM, no lines will appear in the test areas for IgG or IgM, indicating a negative result. However, as a check to ensure that the sample volume used is sufficient and that the procedure has been successful, a third line appears in the control area.  
These types of tests are used for medical diagnosis and home testing, as well as in the lab.
Covid-19 quick test

Covid-19 quick test

A reliable and quality test

Given the importance of results in people’s lives and in the safety of their environments, special attention has been paid to test controls.
In fact, internal controls are included in the test. This is displayed on a colored line appearing in the control region (C) composing the internal control of the procedure. This ensures that the technique carried out is correct and that the sample volume used is sufficient. Control standards are not included in the kit, however, it is recommended to test with negative and positive controls as indicated by good laboratory practices to verify the test result.